EP Dihydroberberine with glucovantage, utilizing our proprietary sustained release vegetable wax matrix technology for maximum bioavailability. Backed with clinical reviews the positively charged berberine is converted in the gut to it's metabolite, dihydroberberine, a neutral charge, a highly bioavailable form to penetrate cells. Pre-clinical research shows berberine activates numerous metabolic and cardiovascular pathways and thereby may help promote glucose balance, healthy cholesterol and lipid metabolism and vascular health.*